| ADM Milling |
| Location: Arkansas City, Kansas ( Cowley ) | Employees:100 | SIC: 3112 |
| Product or Service: Grain Milling | Office function: milling | NAICS: 311211 |
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| City of Arkansas City |
| Location: Arkansas City, Kansas ( Cowley ) | Employees: 113 | SIC: 9111 |
| Product or Service: Municipal Government | Office function: City Government Offices | NAICS: 921110 |
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| City of Winfield |
| Location: Winfield, Kansas ( Cowley ) | Employees: 170 | SIC: 9111 |
| Product or Service: Municipal Government | Office function: City Government Offices | NAICS: 921110 |
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| Columbia Elevator |
| Location: Strother Field, Kansas ( Cowley ) | Employees: 60 | SIC: 33 |
| Product or Service: Manufacturing & Metal Fabrication | Office function: Elevator and cab manufacturing | NAICS: 0 |
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| Cowley College |
| Location: Arkansas City, Kansas ( Cowley ) | Employees: 212 | SIC: 8221 |
| Product or Service: post secondary education | Office function: Community College & Vocational/Technical Education | NAICS: 611310 |
|
| Cowley County |
| Location: Winfield, Kansas ( Cowley ) | Employees: 154 | SIC: 9111 |
| Product or Service: County Government | Office function: Government Offices | NAICS: 921110 |
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| Creekstone Farms Premium Beef |
| Location: Arkansas City, Kansas ( Cowley ) | Employees: 850 | SIC: 3116 |
| Product or Service: Animal Processing | Office function: | NAICS: 311612 |
|
| Galaxy Technologies |
| Location: Winfield, Kansas ( Cowley ) | Employees:153 | SIC: 3335 |
| Product or Service: Manufacturing | Office function: manufacturing | NAICS: 33351 |
|
| GE Aviation |
| Location: Strother Field, Kansas ( Cowley County ) | Employees: 750 | SIC: 4881 |
| Product or Service: Aircraft Engine Maintenance | Office function: Branch | NAICS: 0 |
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| Jet AirWerks |
| Location: Arkansas City, Kansas ( Cowley ) | Employees: 24 | SIC: 4881 |
| Product or Service: Jet Engine Repair | Office function: Jet Engine Repair | NAICS: 0 |
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| Kan-Pak |
| Location: Arkansas City , Kansas ( Cowley ) | Employees:277 | SIC: 0 |
| Product or Service: Aseptic Cold and Frozen Drink Packaging | Office function: Headquarters | NAICS: 3121 |
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| Kansas Veterans Home |
| Location: Winfield (Cowley) Employees: 167 |
| Product or Service: Health Care and Long term care |
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| L.G. Pike Construction Co Inc. |
| Location: Arkansas City (Cowley) Employees: 53 |
| Product or Service: Railway Maintenance |
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| Morton Buildings |
| Location: Strother Field, Kansas ( Cowley ) | Employees: 48 | SIC: 3323 |
| Product or Service: Metal Building Plant | Office function: Plant | NAICS: 0 |
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| Newell Rubbermaid |
| Location: Winfield, Kansas ( Cowley ) | Employees: 800 | SIC: 0 |
| Product or Service: Plastics Manufacturing | Office function: Branch | NAICS: 0 |
|
| S and Y Industries |
| Location: Winfield, Kansas ( Cowley ) | Employees: 100 | SIC: 3679 |
| Product or Service: printed circuit board & wiring harness manufacturing | Office function: electronic assembly | NAICS: 334418 |
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| Skyline Corp |
| Location: Arkansas City, Kansas ( Cowley ) | Employees: 125 | SIC: 3323 |
| Product or Service: Manufactured Homes | Office function: Manufactures Homes-Industry | NAICS: 0 |
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| South Central Kansas Regional Medical Center |
| Location: Arkansas City, Kansas ( Cowley ) | Employees: 215 | SIC: 0 |
| Product or Service: Hospital and Outpatient Services | Office function: Hospital | NAICS: 8062 |
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| Southwestern College |
| Location: Winfield, Kansas ( Cowley ) | Employees: 214 | SIC: 8221 |
| Product or Service: secondary education | Office function: University | NAICS: 611310 |
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| Twin Rivers Developmental Supports |
| Location: Strother Field, Kansas ( Cowley ) | Employees: 77 | SIC: 0 |
| Product or Service: Developmental Disabilities Services | Office function: | NAICS: 0 |
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| United School District No 465 |
| Location: Winfield, Kansas ( Cowley County ) | Employees: 625 | SIC: 8211 |
| Product or Service: Education | Office function: elementary and secondary schools | NAICS: 611110 |
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| United School District No 470 |
| Location: Arkansas City, Kansas ( Cowley ) | Employees: 444 | SIC: 8211 |
| Product or Service: education | Office function: School | NAICS: 0 |
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| Webster Combustion |
| Location: Winfield, Kansas ( Cowley ) | Employees: 63 | SIC: 3324 |
| Product or Service: Boiler, Tank engineering & manufacturing | Office function: manufacturing and engineering | NAICS: 332410 |
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| Western Industries |
| Location: Strother Field, Kansas ( Cowley ) | Employees:195 | SIC: 0 |
| Product or Service: Blow molding Manufacturing | Office function: Branch | NAICS: 3261 |
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| William Newton Memorial Hospital |
| Location: Winfield, Kansas ( Cowley ) | Employees: 310 | SIC: 8062 |
| Product or Service: Hospital and Outpatient Services | Office function: | NAICS: 0 |
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| Winfield Correctional Facility |
| Location: Winfield, Kansas ( Cowley ) | Employees: 200 | SIC: 0 |
| Product or Service: Department of Corrections | Office function: | NAICS: 0 |